AI Identifies New Alzheimer's Protein Target by Analyzing Thousands of Brain Scans

An AI system analyzed thousands of human brain scans and identified Chromogranin A as a key protein in Alzheimer's pathology — a finding that could redirect drug development.

Bryan Johnson flagged a striking AI-in-science result on Wednesday: an AI system that read thousands of human brain scans identified a protein called Chromogranin A as potentially central to Alzheimer's pathology. As @bryan_johnson noted, "20 to 30% of older adults have full blown Alzheimer's pathology" — making any new mechanistic insight enormously valuable.

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